[Bright_Sunday]

“Now, if you are considering using ivermectin on a compassionate basis you must know this:

Ivermectin can cross react with GABA-gated chlorine channels in the C[entral] N[ervous] S[ystem] and cause neurotoxicity. This is normally prevented by the blood brain barrier (BBB), particularly by the P-gp.

If you do not have a fully functional BBB ivermectin may not be the safe drug it usually is.

Now, hyperi[n]flammatory states, such as the one caused by COVID19 make the BBB leaky.

I would be careful to use ivermectin in severely ill patients…” -Dr. Carlos Chaccour

https://twitter.com/Carlos_Chaccour/status/1246432979485949959

Ivermectin-can-cross-reat-with-GABA-gated-chlorine-channels-in-the-CNS-and-cause-neurotoxicity.png 172 KB Image File - Click to view

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